The Adenovirus 5 E1A binding protein Antibody, ALEXA FLUOR® 555 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ZMYND11. This antibody recognizes Rat antigen. The Adenovirus 5 E1A binding protein Antibody, ALEXA FLUOR® 555 Conjugated has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth